Screening Method for PFAS in Solid and Liquid Matrix by C-IC

Polyfluoroalkyl Substances (PFAS) in the Environment
Oral Presentation

Presented by R. Van Wessel
Prepared by R. Van Wessel
TE Instruments USA LLC, 3430 S. Sam Houston Pkwy E #400, Houston, Texas, 77047, United States


Contact Information: robbert.vanwessel@teinstruments.com; +31643842601


ABSTRACT

PFAS are very persistent in the environment and in the human body – meaning they don’t break down and they can accumulate over time. It has been studied that exposure to PFAS can lead to adverse human health effects and many combinations are on the list of “suspect” carcinogenic.
Common Analytical screening and assay methods nowadays are based on an extraction or pre-concentration of sample preparation , followed by LC-MS/MS analysis. To make a clear fingerprint profile of the present PFAS compounds, long analytical separation times are required.
The sample preparation and analytical systems requires high analytical skilled personal to understand the method basics and to keep the equipment in good condition.
By combining the power of combustion analyzers and Ion Chromatography systems (CIC), there is an alternative for a fast and easy screening method for levels of Fluoride in soil and liquid matrices.
With the addition of an Ion Chromatograph, a distinctive separation method between halogens is introduced opening doors to discriminate between all the halogens present in the combustion gas (formed after the pyrolysis).
A CIC method consist of an autosampler, combustion analyzer, absorber unit and a Ion chromatograph (for analysis of the compounds). The combination makes it able to do a relative fast and easy screening of soil or liquid matrix on the present of total bound Fluoride with runtimes of around 20 to 30 minutes per sample.
CIC can be very useful as an pre-screening method beforehand using the current analytical methods.
With CIC (Combustion Ion Chromatography) a limit of detection around 0,2 ppb is achievable (based on 100 ml sample material and preconcentration in 2 ml absorbent), however, research is still ongoing and lower levels have been reported.