Tips to Optimizing Newer Agilent Instrumentation for Semivolatiles Analysis by EPA Method 8270D to Maximize Instrument Up-time Using Split Injection while Minimizing the Loss of Method Sensitivity

Oral Presentation

Prepared by C. Rattray
Restek Corporation, 110 Benner Circle, Bellefonte, PA, 16823, United States

Contact Information: [email protected]; 814-353-1300


Analysis by split injection has many benefits: elevated starting oven temperatures shorten run times and increase throughput while fast sample transfer improves chromatographic performance. Most importantly, inlet discrimination and adsorptive loss are minimized, even after running many dirty samples, extending inlet liner and analytical column life (minimizing downtime). This presentation will demonstrate how reporting limits can be maintained and dynamic calibration ranges extended by optimizing detector settings when split injection is properly implemented.