Achieving Fast, Efficient Separations in Environmental Applications Using Superficially Porous Particle Column Technology

Poster Presentation

Prepared by J. Konschnik
Restek Corporation, 110 Benner Circle, Bellefonte, PA, 16823, United States

Contact Information:; 81435313002494


Superficially porous particles (SPP) have been proven to provide fast and efficient separations. These particles feature a solid, impermeable core enveloped by a thin, porous layer of silica that decreases the diffusion path and reduces peak dispersion. When combined with highly selective stationary phases, the result is significant improvements in efficiency and sensitivity over fully porous particles (FPP) of similar dimension. With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (SPP) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. The versatility of these columns makes them ideal for separations for a variety of environmental applications.

The performance of SPP particle columns will be demonstrated on a variety of applications, including bisphenol A, pesticides, and perfluorinated alkyl acids using simple mobile phases and gradient methods. For example, in order to analyze large lists of compounds, especially across multiple classes, your column must be capable of spreading analytes out over the gradient to ensure accurate detector response and quantitation. In designing the Raptor™ ARC-18 column, we adjusted our bonding procedures to form an ideal ligand density that offers balanced retention for the rapid analysis of large, multiclass assays. With its balanced retention profile, the Raptor™ ARC-18 column is ideally suited to analyze a 204-compound pesticide screen in just 9.5 minutes

Restek LC columns offer the speed of superficially porous particles with the resolution of the highly selective stationary phases, allowing peak separation and faster analysis times to be achieved without expensive UHPLC instrumentation.