Advanced Chromatography and Workflow Options for Perfluoroalkyl Substance Analysis (PFAS) in Drinking Water, Sediments and Food Samples by QuEChERS, SPE and LC-MS/MS

Poster Presentation

Prepared by , A. Misa

Contact Information:; 310-212-0555


Perfluroalkyl Substances (PFASs) are synthetic organofluorine compounds which are bioaccumulative and extremely resistant to degradation due to heat, acids, or bases. Human exposure to residues has been implicated in the incidence of obesity, cancer, endocrine system disruption, and other adverse health effects. In the recent year due to the US EPA health advisory issued in May 2016 at 70 ng/L in drinking water It has received much attention. PFAS are present in a variety of products—including food packaging, textiles, and fire-fighting foams—and have been detected in the environment as well as in the blood of the general population.

Due to its persistence and high bioaccumulative nature, questions have been presented in whether they are being passed on to livestock along with other food products as the water supply and environmental exposure eventually leads to food supply. Presented are various workflows for the extraction and analysis of Perfuoroalkyl Substances in water as well as food samples using advancements in sample preparation techniques as well as chromatographic improvments coupled by LC-MS/MS. Samples such as drinking water, sediments, butter, and eggs.