Advantages of In-line Dilution on LC-ICP-MS Based Applications

Metals and Metals Speciation Analysis in Environmental Samples
Oral Presentation

Prepared by

Contact Information:; 402-991-7800


Depending on the species present, the influence of a metal ion or metal complex within an environment or biological system can be essential or toxic. It is well established that methods exist in the literature on how to differentiate and detect essential and toxic species. Typically, a gas chromatography (GC) or liquid chromatography (LC) system is coupled to an Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) instrument. While these instruments continue to improve, there is still one major issue that continues to be debated: Is the integrity of the sample maintained from sample preparation to final analysis.
The prepFAST IC is a syringe driven LC system that can be connected to any ICP-OES or ICP-MS and is capable of inline dilution for calibration and sample preparation. The following presentation will look at advantages for using inline dilutions to preserve samples for both metal speciation and total metals analysis. The applications investigated will include arsenic and chromium for both speciation and total metals analysis.