Flexible, Wearable Diamond-Based Sensors for Assessment of Lead and Copper Exposure in Sweat: Device Fabrication and Electrochemical Characterization
Academic Research Topics in Environmental Measurement and Monitoring
Oral Presentation
Prepared by C. Rusinek1, M. Becker1, J. Hill2
1 - Michigan State University- Fraunhofer USA, Inc. Center for Coatings and Diamond Technologies, 1449 Engineering Research Ct., East Lansing, Michigan - MI, 48824, United States
2 - Bioanalytical Systems, Inc., 2701 Kent Ave., West Lafayette, IN, 47906, United States
Contact Information: crusinek@fraunhofer.org; 517-884-8694
ABSTRACT
Real-time monitoring of toxic heavy metal concentrations in biological fluids such as perspiration, saliva, and urine enables a rapid, non-invasive method to assess exposure. Electrochemical sensing offers attractive advantages as a tool for exposure assessment: low cost of instrumentation, high sensitivity, portability, and ease of miniaturization. Many different electrode materials have been used for toxic heavy metal sensing and some as flexible devices. The materials used for these devices, however, suffer from limited working potential windows and are easily prone to fouling; boron-doped diamond (BDD) has the potential to surpass the performance of these materials. Though BDD-based electrochemical sensors have shown a significant degree of promise, current devices have fundamental limitations in mechanical flexibility and device scalability. To overcome these challenges, we developed a flexible, wearable BDD sensing package using innovative diamond processing techniques, precise device construction methods. This presentation will outline the BDD device fabrication and electrochemical characterization with the ultimate goal of sweat-based sensing. Measurements of lead (Pb), copper (Cu), manganese (Mn), and zinc (Zn) were simultaneously measured in artificial perspiration. This research could lead to broad applicability for non-invasive exposure assessment to toxic heavy metals.
Academic Research Topics in Environmental Measurement and Monitoring
Oral Presentation
Prepared by C. Rusinek1, M. Becker1, J. Hill2
1 - Michigan State University- Fraunhofer USA, Inc. Center for Coatings and Diamond Technologies, 1449 Engineering Research Ct., East Lansing, Michigan - MI, 48824, United States
2 - Bioanalytical Systems, Inc., 2701 Kent Ave., West Lafayette, IN, 47906, United States
Contact Information: crusinek@fraunhofer.org; 517-884-8694
ABSTRACT
Real-time monitoring of toxic heavy metal concentrations in biological fluids such as perspiration, saliva, and urine enables a rapid, non-invasive method to assess exposure. Electrochemical sensing offers attractive advantages as a tool for exposure assessment: low cost of instrumentation, high sensitivity, portability, and ease of miniaturization. Many different electrode materials have been used for toxic heavy metal sensing and some as flexible devices. The materials used for these devices, however, suffer from limited working potential windows and are easily prone to fouling; boron-doped diamond (BDD) has the potential to surpass the performance of these materials. Though BDD-based electrochemical sensors have shown a significant degree of promise, current devices have fundamental limitations in mechanical flexibility and device scalability. To overcome these challenges, we developed a flexible, wearable BDD sensing package using innovative diamond processing techniques, precise device construction methods. This presentation will outline the BDD device fabrication and electrochemical characterization with the ultimate goal of sweat-based sensing. Measurements of lead (Pb), copper (Cu), manganese (Mn), and zinc (Zn) were simultaneously measured in artificial perspiration. This research could lead to broad applicability for non-invasive exposure assessment to toxic heavy metals.
