Analysis of PCB Arochlors Utilizing GC Tandem Mass Spectrometry

Poster Presentation

Prepared by D. Walker, J. Weitzel
Agilent Technologies, 2850 Centerville Road, Wilmington, Delaware, 19808

Contact Information: Dale.Walker@agilent.com; 916-458-2940

ABSTRACT

The poster demonstrates the applicability of GC tandem mass spectrometry to monitor exposure to PCB Arochlors in matrix. The same methodology is also applied to matrices such as gas-phase air, particulate phase air, sediment and sediment pore water. Human health studies concluded that PCB Arochlors are probable carcinogens and exposure can also result in deleterious effects on the immune, reproductive and endocrine systems.

Traditionally the analysis for PCB Arochlors is done by GC Electron Capture Detector (ECD) methodology. Historically a traditional single stage GCMS system has lacked the ability to achieve the detection limits of an ECD due to matrix interferences.

In this study we employed the use of a GC-tandem mass spectrometry (GC-MS/MS) The GC-MS/MS not only achieved but surpassed the required detection limits of the traditional GC ECD detector. In addition to achieving the detection limits the system also offers confirmation of the compound by using the individual Congener groups to positively identify the compounds by utilizing both the GC retention times and the MRM transition for the Arochlor. Comparing the data with that obtained via GC-ECD suggests that GC-MS/MS is an appropriate tool and offers a confirmatory technique. Labs may now expand GC-MS/MS for the analysis of PCB Arochlors in matrix.

(Related Session: Operational and Advocacy Issues Impacting the Environmental Laboratory Industry)